Column composition - interleave 2,

- 78 - ?

285AAAAAAAAAUGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-

AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA- - 79 - ?

GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-

UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUU-

289AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA-

290AAAAAUGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-

AAUGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-

AAAAAAAAAAUUUUUUUGGGGGGGGGGGGGGGGGGGGGC-

UCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC- - 80 - H375

AGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-

AAGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-

AAAAGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGCC-

AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAGGGGGGGGG-

298CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC-

299AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA-

300 CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC-

UGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG- - 81 - ?

AAAAAAAAAAUUUUUUUUUUUUUUUUUUUUUUUUUUUUC-

GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-

AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAUUUUUGGGG-

305AAAAAAAAAAAAAAAAAAAAUUUUUUUUUUUUUUUCCCC-

306AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA-

UUUUUUUUUUUUUUUUUUUUUUUUUUUUUCCCCCCCCCC-

UUUUGGCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC-

U---------------------------------------

310 UUUUUUUUUUUUUUUUCCCCCCCCCCCCCCCCCCCCCCC- - 82 - H375'

UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUC-

UGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-

AAAAAAAUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUG-

AUUUUUUUUUCCCCCCCCCCCCCCCCCCCCCCCCCCCCC-

315AUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUC-

316GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-

AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA-

AUUUUUUUUUUUUUUUUUUUUUUUGGGGGGGGGCCCCCC-

320 AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAGC-

A---------------------------------------

U---------------------------------------

C---------------------------------------

U---------------------------------------

----------------------------------------

---------------------------------------- - 83 - ?

C---------------------------------------

U---------------------------------------

A---------------------------------------

330 C---------------------------------------

A---------------------------------------

G---------------------------------------

A---------------------------------------

G---------------------------------------

A---------------------------------------

G---------------------------------------

337AUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUC-

338AAGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-

GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG- - 84 - H406

340 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-

AUGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-

342AGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-

343GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG- - 85 - ?

344AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAUC-

345CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC-

CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC- - 86 - H413

AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA-

348UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUCC-

349UCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC-

350 AUCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC- - 87 - H406'

UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUU-

CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC-

353UUCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC-

354AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA- - 88 - ?

355AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA-

356GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-

GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGC- - 89 - H265'

CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC-

359UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUU-

360AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA- - 90 - ?

361AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA-

362AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAG- - 91 - H234'

363UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUU- - 92 - ?

364AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA-

365CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC-

UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUG-

AAAAAAAUCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC-

AUUGGCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC-

UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUCCCCC-

370 AAAAAUUUUUGGGGGGGGGGGGGGGGGGGGGGGGGGGGC- - 93 - H35'

AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAUGGGC-

AAUUUUUUGCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC-

UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUGCCCCC-

AGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-

AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA-

UGCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC-

377CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC-

378GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-

AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA-

380 UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUU-

AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA-

GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-

UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUC-

GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG- - 94 - ?

AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAC-

AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA-

CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC-

AUUUUUGCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC-

AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA-

390 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-

UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUU-

392AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA-

393CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC- - 95 - H461

394UUCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC-

395GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-

UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUU- - 96 - ?

AGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-

398AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA-

399AAGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG- - 97 - H461'

400 400GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-

401GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-

AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA- - 98 - ?

AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA-

404AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA-

405AGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG- - 99 - H31'

406AGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-

407UUUUCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC-

GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-

AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA-

410 AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA-

AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA- - 100 - ?

AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA-

A---------------------------------------

GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-

AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAUC-

416AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA-

417CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC-

CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC- - 101 - H484

UGCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC-

420 420UCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC-

421UUUUUUUUUUUUUUUUGGGGGGGGGGGGGGGGGGGGGGG-

AUGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG- - 102 - ?

AAAAAAAAUUUUUUUUUUUUUUUUUUUUUUUCCCCCCC--

AUGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-

425AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA-

426AUGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-

AGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGC- - 103 - H484'

GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-

429GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-

430AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA-

GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-

UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUU-

GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-

AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA-

AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA- - 104 - ?

AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA-

AUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUGC-

AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA-

GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-

440 AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA-

AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAUUUUUUUC-

442UCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC-

443CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC-

UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUU-

AGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-

----------------------------------------

AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA-

450 UCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC- - 105 - H15'

UCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC-

AUGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGC-

AUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUGC-

AAAAAAAAAAAAAAAAAUGGGGGGGGGGGGGGGGGGGGC-

UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUG-

AAAAAAAAAAAAAAAAAAAAAAAGGGGGGGGGGGGGGGG-

CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC-

AAGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGC-

459UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUU-

460AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA-

ACCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC- - 106 - ?

AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA-

464AUGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-

465CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC- - 107 - H531

466AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA- - 108 - ?